Which of the following regimen is appropriate for a patient who previously completed treatment for DS-TB and shows symptoms of PTB?

In the context of tuberculosis treatment, particularly for a patient who has previously completed treatment for drug-susceptible tuberculosis (DS-TB) and is now presenting with symptoms of pulmonary tuberculosis (PTB), the appropriate regimen is the 2HRZE/4HR regimen.

This regimen is based on the well-established principles of tuberculosis management, which involve an intensive phase and a continuation phase. The initial phase (2 months) includes a combination of four first-line antitubercular drugs: isoniazid (H), rifampicin (R), pyrazinamide (Z), and ethambutol (E). This combination has shown effectiveness in rapidly reducing the bacterial load. After the intensive phase, the continuation phase lasts for an additional four months with rifampicin and isoniazid alone.

The choice of this specific regimen for a patient with a previous history of DS-TB is important because it ensures a comprehensive treatment approach with effective medication that targets the bacteria while minimizing the risk of resistance development. The regimen is streamlined and is recommended to avoid complications and better manage potential recurrence.

Other choices are not as suitable for this scenario; for example, the 6HRZE regimen consists of a different combination and duration